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You may know by now that drugs release a copious amount of dopamine to the brain, a chemical that makes the brain transmit a feeling of pleasure. But what you may not understand is that the brain will start to make less dopamine or will reduce the amount of receptors that can get signals, because of the increased levels of dopamine introduced by the drug.
Because of this, when the user stops taking the drug, dopamine can become unusually low, and the brain’s ability to record pleasure is stunted. Then the user will often become depressed and will not get pleasure from those things that used to be enjoyable.
Then the user needs to take the drug so that the dopamine in the brain will be at a normal level. Then tolerance develops, as the user needs to have increasingly larger doses of the drug to get that rush — or the high they experienced when first taking the drug.
Scientific studies reveal that continued drug use makes significant changes in the neurons of the brain and can cause permanent damage. For instance, when the level of a neurotransmitter called glutamate is changed because of a drug, users do not learn as well. Glutamate is involved in the brain’s ability to learn.
Drug abuse can also cause long-term damage to memory as well. In addition, as many may know, drug abuse loosens inhibitions. An addict often will engage in very risky behaviors because drugs affect self-control and impair the user’s ability to make safe decisions.
Who hasn’t seen colleagues who have had a few too many drinks at the office party embarrass themselves and others with behavior they regret later? For an addict, this loss of control becomes a way of life — and when in the throes of physical addiction, the need for the drug takes over, and even regret flies out the window.






